Primary sclerosing cholangitis causing intrahepatic cholestasis – morning report 7.31.2019

Today at morning report we had an interesting case of young patient with jaundice, pruritus, abdominal pain and weight loss. ANCA was positive. Following liver biopsy and MRCP the patient was diagnosed with primary sclerosing cholangitis and ultimately with Crohn's. We also discussed this great article from NEJM about DILI (nejmra1816149) which describes 3 patterns … Continue reading Primary sclerosing cholangitis causing intrahepatic cholestasis – morning report 7.31.2019

Abdominal Pain and Hypercoagulability – Morning Report 7.24.19

Today at Morning Report we discussed a patient who had a family history of thrombotic events, presenting with acute onset and worsening abdominal pain and later found to have superior mesenteric vein and portal vein thrombosis. Remember, acute mesenteric vein thrombosis presents similar to other mesenteric ischemias with non-specific central, peri-umbilical abdominal pain, classically described … Continue reading Abdominal Pain and Hypercoagulability – Morning Report 7.24.19

Lithium Toxicity – Morning report (7/10/19)

Today we had a interesting case of lithium toxicity with normal blood levels in an elderly patient. This interesting article describes the possible mechanism for it which we mentioned this morning: "In patients taking chronically high doses, lithium will accumulate at a level in CNS tissue that induces toxicity. If subsequent doses are missed, the … Continue reading Lithium Toxicity – Morning report (7/10/19)

All in the head. Morning Report 1.9.2019

At morning report we discussed a case of a woman who presented with 1 month of progressively worsening headaches, chills and diaphoresis. She had a 150pack year smoking history and was found to have metastatic adenocarcinoma with brain mets. Interestingly, she was also found to have an adrenal nodule and was noted to have very … Continue reading All in the head. Morning Report 1.9.2019